Sorensen, D., Danish Institute of Agricultural Sciences, Tjele, Denmark;
Gianola, D., University of Wisconsin, Madison, WI, USA

Likelihood, Bayesian and MCMC Methods in Genetics

2002. Approx. 735 pp. Hardcover
0-387-95440-6

Over the last ten years the introduction of computer intensive statistical methods has opened new horizons concerning the probability models that can be fitted to genetic data, the scale of the problems that can be tackled and the nature of the questions that can be posed. In particular, the application of Bayesian and likelihood methods to statistical genetics has been facilitated enormously by these methods. Techniques generally referred to as Markov chain Monte Carlo (MCMC) have played a major role in this process, stimulating synergies among scientists in different fields, such as mathematicians, probabilists, statisticians, computer scientists and statistical geneticists. Specifically, the MCMC "revolution" has made a deep impact in quantitative genetics. This can be seen, for example, in the vast number of papers dealing with complex hierarchical models and models for detection of genes affecting quantitative or meristic traits in plants, animals and humans that have been published recently.
This book, suitable for numerate biologists and for applied statisticians, provides the foundations of likelihood, Bayesian and MCMC methods in the context of genetic analysis of quantitative traits. Most students in biology and agriculture lack the formal background needed to learn these modern biometrical techniques. Although a number of excellent texts in these areas have become available in recent years, the basic ideas and tools are typically described in a technically demanding style, and have been written by and addressed to professional statisticians. For this reason, considerable more detail is offered than what may be warranted for a more mathematically apt audience.
The book is divided into four parts. Part I gives a review of probability and distribution theory. Parts II and III present methods of inference and MCMC methods. Part IV discusses several models that can be applied in quantitative genetics, primarily from a bayesian perspective. An effort has been made to relate biological to statistical parameters throughout, and examples are used profusely to motivate the developments.

Contents: Probability and Random Variables.- Functions of Random Variables.- An Introduction to Likelihood Inference.- Further Topics in Likelihood Inference.- An Introduction to Bayesian Inference.- Bayesian Analysis of Linear Models.- The Prior Distribution and Bayesian Analysis.- Bayesian Assessment of Hypotheses and Models.- Approximate Methods of Inference: The EM Algorithm.- An Overview of Discrete Markov Chains.- Markov Chain Monte Carlo.- Analysis of MCMC Samples.- Gaussian and Thick-tailed Linear Models.- Analyses Involving Ordered Categorical Traits.- Bayesian Analysis of Longitudinal Data.- Segregation and the QTL Analysis.

Series: Statistics for Biology and Health.

Valiente, G., Technical University of Barcelona, Spain

Algorithms on Trees and Graphs

2002. XI, 510 pp. Hardcover
3-540-43550-6

Graph algorithms is a well-established subject in mathematics and computer science. Beyond classical application fields, like approximation, combinatorial optimization, graphics, and operations research, graph algorithms have recently attracted increased attention from computational molecular biology and computational chemistry. Centered around the fundamental issue of graph isomorphism, this text goes beyond classical graph problems of shortest paths, spanning trees, flows in networks, and matchings in bipartite graphs. Advanced algorithmic results and techniques of practical relevance are presented in a coherent and consolidated way. This book introduces graph algorithms on an intuitive basis followed by a detailed exposition in a literate programming style, with correctness proofs as well as worst-case analyses. Furthermore, full C++ implementations of all algorithms presented are given using the LEDA library of efficient data structures and algorithms. Numerous illustrations, examples, and exercises, and a comprehensive bibliography support students and professionals in using the book as a text and source of reference

Keywords: Graph algorithms, graph isomorphism, tree isomorphism, computational biology, computational chemistry, literate programming, computational graph theory, combinatorial algorithms, algorithmic graph theory

Contents: Preface.- Part I. Introduction: 1. Introduction. 2. Algorithmic Techniques.- Part II. Algorithms on Trees: 3. Tree Traversal. 4. Tree Isomorphism.- Part III. Algorithms on Graphs: 5. Graph Traversal. 6. Clique, Independent Set, and Vertex Cover. 7. Graph Isomorphism; Appendices: A. An Overview of Leda. B. Interactive Demonstration of Graph Algorithms. C. Program Modules. - References.- Index.

Venables, W.N., CSIRO Marine Laboratories, Cleveland, Qld., Australia;
Ripley, B.D., University of Oxford, UK

Modern Applied Statistics with S, 4th ed.

2002. Approx. 515 pp. 144 figs. Hardcover
0-387-95457-0

S is a powerful environment for the statistical and graphical analysis of data. It provides the tools to implement many statistical ideas that have been made possible by the widespread availability of workstations having good graphics and computational capabilities. This book is a guide to using S environments to perform statistical analyses and provides both an introduction to the use of S and a course in modern statistical methods. Implementations of S are available commercially in S-PLUS(R) workstations and as the Open Source R for a wide range of computer systems.
The aim of this book is to show how to use S as a powerful and graphical data analysis system. Readers are assumed to have a basic grounding in statistics, and so the book is intended for would-be users of S-PLUS or R and both students and researchers using statistics. Throughout, the emphasis is on presenting practical problems and full analyses of real data sets. Many of the methods discussed are state of the art approaches to topics such as linear, nonlinear and smooth regression models, tree-based methods, multivariate analysis, pattern recognition, survival analysis, time series and spatial statistics. Throughout modern techniques such as robust methods, non-parametric smoothing and bootstrapping are used where appropriate.
This fourth edition is intended for users of S-PLUS 6.0 or R 1.5.0 or later. A substantial change from the third edition is updating for the current versions of S-PLUS and adding coverage of R. The introductory material has been rewritten to emphasis the import, export and manipulation of data. Increased computational power allows even more computer-intensive methods to be used, and methods such as GLMMs, MARS, SOM and support vector machines are considered.

Contents: Introduction.- Data Manipulation.- The S Language.- Graphics.- Univariate Statistics.- Linear Statistical Models.- Generalized Linear Models.- Non-linear and Smooth Regression.- Tree-based Methods.- Random and Mixed Effects.- Exploratory Multivariate Analysis.- Classification.- Survival Analysis.- Time Series Analysis.- Spatial Statistics.- Optimization.

Series: Statistics and Computing.

Serre, D., Ecole Normale Superieure de Lyon, France

Matrices
Theory and Applications

2002. Approx. 200 pp. Hardcover
0-387-95460-0

In this book, Denis Serre begins by providing a clean and concise introduction to the basic theory of matrices. He then goes on to give many interesting applications of matrices to different aspects of mathematics and also other areas of science and engineering. The book mixes together algebra, analysis, complexity theory and numerical analysis. As such, this book will provide many scientists, not just mathematicians, with a useful and reliable reference. It is intended for advanced undergraduate and graduate students with either applied or theoretical goals. This book is based on a course given by the author at the Ecole Normale Superieure de Lyon.
Denis Serre is Professor of Mathematics at Ecole Normale Superieure de Lyon and a former member of the Institut Universaire de France. He is a member of numerous editorial boards and the author of Systems of Conservation Laws (Cambridge University Press 2000). The present book is a translation of the original French edition, Les Matrices: Theorie et Pratique, published by Dunod (2001).

Contents: Elementary Theory.- Square Matrices.- Matrices with Real or Complex Entries.- Norms.- Non-negative Matrices.- Matrices with Entries in a Principal Domain.- Jordan's Reduction.- Exponential of a Matrix, Polar Decomposition and Classical Groups.- Matrix Factorizations.- Iterative Methods for Linear Problems.- Approximation of Eigenvalues.- Bibliography.- Index.- List of Symbols.

Series: Graduate Texts in Mathematics. VOL. 216

Audin, M., Universite Louis Pasteur, Strasbourg, France

Geometry

2002. VI, 357 pp. 172 figs. Softcover
3-540-43498-4

Geometry, this very ancient field of study of mathematics, frequently remains too little familiar to students. Michele Audin, professor at the University of Strasbourg, has written a book allowing them to remedy this situation and, starting from linear algebra, extend their knowledge of affine, Euclidean and projective geometry, conic sections and quadrics, curves and surfaces.
It includes many nice theorems like the nine-point circle, Feuerbach's theorem, and so on. Everything is presented clearly and rigourously. Each property is proved, examples and exercises illustrate the course content perfectly. Precise hints for most of the exercises are provided at the end of the book. This very comprehensive text is addressed to students at upper undergraduate and Master's level to discover geometry and deepen their knowledge and understanding.

Keywords: Euclidean geometry, projective geometry, conics, quadrics, differential geometry 51XX, 53XX

Contents: Introduction.- Affine geometry.- Euclidean geometry, generalities.- Euclidean geometry in the plane.- Euclidean geometry in space.- Projective geometry.- Conics and quadrics.- Curves, envelopes, evolutes.- Surfaces in the dimension-3 space.- A few hints and solutions to exercises.- Bibliography.- Index

Series: Universitext.

Marker, D., University of Illinois, Chicago, IL, USA

Model Theory: An Introduction

2002. Approx. 340 pp. 2 figs. Hardcover
0-387-98760-6

This book is a modern introduction to model theory which stresses applications to algebra throughout the text. The first half of the book includes classical material on model construction techniques, type spaces, prime models, saturated models, countable models, and indiscernibles and their applications. The author also includes an introduction to stability theory beginning with Morley's Categoricity Theorem and concentrating on omega-stable theories. One significant aspect of this text is the inclusion of chapters on important topics not covered in other introductory texts, such as omega-stable groups and the geometry of strongly minimal sets. The author then goes on to illustrate how these ingredients are used in Hrushovski's applications to diophantine geometry.

David Marker is Professor of Mathematics at the University of Illinois at Chicago. His main area of research involves mathematical logic and model theory, and their applications to algebra and geometry. This book was developed from a series of lectures given by the author at the Mathematical Sciences Research Institute in 1998.

Contents: Part A: Structures and Theories. Basics. Algebraic Examples.- Part B: Realizing and Omitting types. Indiscernibles.- Part C: Categoricity. Omega-stable groups. Geometry of Strongly Minimal Sets.- Appendices.

Series: Graduate Texts in Mathematics. VOL. 217

Langtangen, H.P., University of Oslo, Norway

Computational Partial Differential Equations, 2nd ed.
Numerical Methods and Diffpack Programming

2002. XXVI, 838 pp. Hardcover
3-540-43416-X

The target audience of this book is students and researchers in computational sciences who need to develop computer codes for solving partial differential equations. The exposition is focused on numerics and software related to mathematical models in solid and fluid mechanics. The book teaches finite element methods, and basic finite difference methods from a computational point of view. The main emphasis regards development of flexible computer programs, using the numerical library Diffpack. The application of Diffpack is explained in detail for problems including model equations in applied mathematics, heat transfer, elasticity, and viscous fluid flow. Diffpack is a modern software development environment based on C++ and object-oriented programming. All the program examples, as well as a test version of Diffpack, are available for free over the Internet. The second edition contains several new applications and projects, improved explanations, correction of errors, and is up to date with Diffpack version 4.0.

Keywords: Diffpack, partial differential equations, computation, programming

Series: Texts in Computational Science and Engineering. VOL. 1