Klein, J. P., Medical College of Wisconsin, Milwaukee, WI, USA; Moeschberger, M. L., Ohio State University, Columbus, OH, USA

Survival Analysis 2nd ed.
Techniques for Censored and Truncated Data

2003 XV, 536 p. 97 illus. Hardcover
0-387-95399-X

Applied statisticians in many fields must frequently analyze time to event data. While the statistical tools presented in this book are applicable to data from medicine, biology, public health, epidemiology, engineering, economics, and demography, the focus here is on applications of the techniques to biology and medicine. The analysis of survival experiments is complicated by issues of censoring, where an individual's life length is known to occur only in a certain period of time, and by truncation, where individuals enter the study only if they survive a sufficient length of time or individuals are included in the study only if the event has occurred by a given date. The use of counting process methodology has allowed for substantial advances in the statistical theory to account for censoring and truncation in survival experiments. This book makes these complex methods more accessible to applied researchers without an advanced mathematical background. The authors present the essence of these techniques, as well as classical techniques not based on counting processes, and apply them to data. Practical suggestions for implementing the various methods are set off in a series of Practical Notes at the end of each section. Technical details of the derivation of the techniques are sketched in a series of Technical Notes. This book will be useful for investigators who need to analyze censored or truncated life time data, and as a textbook for a graduate course in survival analysis. The prerequisite is a standard course in statistical methodology.

Contents: Examples of Survival Data.- Basic Quantities and Models.- Censoring and Truncation.- Nonparametric Estimation of Basic Quantities for Right-Censored and Left-Truncated Data.- Estimation of Basic 1= Quantities for Other Sampling Schemes.- Topics in Univariate Estimation.- Hypothesis Testing.- Semiparametric Proportional Hazards Regression with Fixed Covariates.- Refinements of the Semiparametric Proportional Hazards Model.- Additive Hazards Regression Models.- Regression Diagnostics.- Inference for Parametric Regression Models.- Multivariate Survival Analysis.

Series: Statistics for Biology and Health.


Grunbaum, B., University of Washington, Seattle, WA, USA

Convex Polytopes 2nd ed.

2003 Approx. 560 p. 162 illus. Hardcover
0-387-00424-6

The appearance of Gruenbaum's book Convex Polytopes in 1967 was a moment of grace to geometers and combinatorialists. The special spirit of the book is very much alive even in those chapters where the book's immense influence made them quickly obsolete. Some other chapters promise beautiful unexplored land for future research. The appearance of the new edition is going to be another moment of grace. Kaibel, Klee and Ziegler were able to update the convex polytope saga in a clear, accurate, lively, and inspired way. --Gil Kalai, The Hebrew University of Jerusalem The original book of Gruenbaum has provided the central reference for work in this active area of mathematics for the past 35 years...I first consulted this book as a graduate student in 1967; yet, even today, I am surprised again and again by what I find there. It is an amazingly complete reference for work on this subject up to that time and continues to be a major influence on research to this day. --Louis J. Billera, Cornell University The original edition of Convex Polytopes inspired a whole generation of grateful workers in polytope theory. Without it, it is doubtful whether many of the subsequent advances in the subject would have been made. The many seeds it sowed have since grown into healthy trees, with vigorous branches and luxuriant foliage. It is good to see it in print once again. --Peter McMullen, University College London

Contents: * Preface * Notation and prerequisites * Convex sets * Polytopes * Examples * Fundamental properties and constructions * Polytopes with few vertices * Neighborly polytopes * Euler's relation * Analogues of Euler's relation * Extremal problems concerning numbers of faces * Properties of boundary complexes * k-Equivalence of polytopes * 3- Polytopes * Angle-sums relations; the Steiner point * Addition and decomposition of polytopes (by G.C. Shephard) * Diameters of Polytopes (by Victor Klee) * Long paths and cicuits on polytopes (by Victor Klee) * Arrangements of hyperplanes * Concluding remarks * Tables * Addendum * Errata * Bibliography * Index of terms * Index of symbols

Series: Graduate Texts in Mathematics. Volume. 221

Arveson, W., University of California at Berkeley, CA, USA

Noncommutative Dynamics and E-Semigroups

2003 Approx. 440 p. Hardcover
0-387-00151-4

This book introduces the notion of an E-semigroup, a generalization of the known concept of E_O-semigroup. These objects are families of endomorphisms of a von Neumann algebra satisfying certain natural algebraic and continuity conditions. This monograph will be of interest to graduate students and research mathematicians.

Contents: Preface * Dynamical Origins * Part 1: Index and Perturbation Theory * E-semigroups * Continuous Tensor Products * Spectral C*-algebras * Part 2: Classification: Type I Cases * Path Spaces * Decomposable Product Systems * Part 3: Noncommutative Laplacians * CP-semigroups * C*-Generators and Dilation Theory * Index Theory for CP-Semigroups * Bounded Generators * Part 4: Causality and Dynamics * Pure Perturbations of CAR/CCR Flows * Interaction Theory * Part 5: Type III Examples * Powers' Examples * Tsirelson-Vershik Product Systems * Bibliography * Index

Series: Springer Monographs in Mathematics.

Fan, J., Chinese University of Hong, Shatin, Hong Kong; Yao, Q., London School of Economics, London, UK

Nonlinear Time Series
Nonparametric and Parametric Methods

2003 Approx. 575 p. 103 illus. Hardcover
0-387-95170-9

This is the first book that integrates useful parametric and nonparametric techniques with time series modeling and prediction, the two important goals of time series analysis. A distinct feature of this book is that it applies many modern nonparametric estimation and testing ideas to time series modeling and model identification, while outlines many useful ideas from more traditional time series analysis. This will enable readers to use modern data-analytic techniques while keeping in touch with traditional approaches, and make the book self-contained. Such a book will benefit researchers and practitioners in various fields such as econometricians, meteorologists, biologists, among others who wish to learn useful time series methods within a short period of time. The book also intends to serve as a reference or text book for graduate students in statistics and econometrics.

Contents: Introduction.- Stationary Time Series.- Smoothing in Time Series.- ARMA Modeling and Forecasting.- Parametric Nonlinear Time Series Models.- Nonparametric Models.- Hypothesis Testing.- Continuous Time Models in Finance.- Nonlinear Prediction.

Series: Springer Series in Statistics.

Parmigiani, G., The Johns Hopkins University, Baltimore, MD, USA; Garett, E. S., The Johns Hopkins University, Baltimore, MD, USA; Irizarry, R. A., The Johns Hopkins University, Baltimore, MD, USA (Eds.)

The Analysis of Gene Expression Data
Methods and Software

2003 Approx. 480 p. 154 illus. Hardcover
0-387-95577-1

This book presents practical approaches for the analysis of data from gene expression microarrays. Each chapter describes the conceptual and methodological underpinning for a statistical tool and its implementation in software. Methods cover all aspects of statistical analysis of microarrays, from annotation and filtering to clustering and classification. Chapters are written by the developers of the software. All software packages described are free to academic users. The book includes coverage of various packages that are part of the Bioconductor project and several related R tools.

The materials presented cover a range of software tools designed for varied audiences. Some chapters describe simple menu-driven software in a user-friendly fashion, and are designed to be accessible to microarray data analysts without formal quantitative training. Most chapters are directed at microarray data analysts with master-level training in computer science, biostatistics or bioinformatics. A minority of more advanced chapters are intended for doctoral students and researchers.

Contents: Introduction.- Visualization and annotation of genomic experiments.- Bioconductor R packages for exploratory data analysis and normalization of cDNA microarray data.- An R package for analyses of affymetrix oligonucleotide arrays.- DNA-Chip analyzer (d-Chip).- Expression Profiler.- An S-Plus library for the analysis of microarray data.- DRAGON and DRAGON View: Methods for the annotation, analysis, and visualization of large-scale gene expression data.- SNOMAD: User-friendly web tools for the standardization and normalization of microarry data.- Microarray analysis using the MicroArray Explorer.- Parametric empirical Bayes methods for microarrays.- SAM thresholding and false discovery rates for detecting differential gene expression in DNA microarrays.- Adaptive gene picking with microarray data: Detecting important low abundance signals.-MAANOVA: A software package for the analysis of spotted cDNA microarray experiments.- GeneClust.- POE Statistical Tools for molecular profiling.- Bayesian decomposition.- Cluster analysis of gene expression dynamics.- Relevance networks: A first step towards finding genetic regulatory networks within microarray data.

Series: Statistics for Biology and Health.


Phillips, G. M., University of St. Andrews, UK

Interpolation and Approximation by Polynomials

2003 Approx. 330 p. 22 illus. Hardcover
0-387-00215-4

This book covers the main topics concerned with interpolation and approximation by polynomials. This subject can be traced back to the precalculus era but has enjoyed most of its growth and development since the end of the nineteenth century and is still a lively and flourishing part of mathematics. In addition to coverage of univariate interpolation and approximation, the text includes material on multivariate interpolation and multivariate numerical integration, a generalization of the Bernstein polynomials that has not previously appeared in book form, and a greater coverage of Peano kernel theory than is found in most textbooks. There are many worked examples and each section ends with a number of carefully selected problems that extend the student's understanding of the text. George Phillips has lectured and researched in mathematics at the University of St. Andrews, Scotland. His most recent book, Two Millenia of Mathematics: From Archimedes to Gauss (Springer 2000), received enthusiastic reviews in the USA, Britain and Canada. He is well known for his clarity of writing and his many contributions as a researcher in approximation theory.

Contents: * Preface * Univariate Interpolation * Best Approximation * Numerical Integration * Peano's Theorem and Applications * Multivariate Interpolation * Splines * Bernstein Polynomials * Properties of the q- integers * References * Index *

Series: CMS Books in Mathematics. Volume. 14

Bloch, A., University of Michigan, Ann Arbor, MI, USA

Nonholonomic Mechanics and Control

2003 Approx. 505 p. 49 illus. Hardcover
0-387-95535-6

The goal of this book is to explore some of the connections between control theory and geometric mechanics; that is, control theory is linked with a geometric view of classical mechanics in both its Lagrangian and Hamiltonian formulations and in particular with the theory of mechanical systems subject to motion constraints. The synthesis of the topic is appropriate as there is a particularly rich connection between mechanics and nonlinear control theory. The aim is to provide a unified treatment of nonlinear control theory and constrained mechanical systems that incorporates material that has not yet made its way into texts and monographs. This book is intended for graduate students who wish to learn this subject and researchers in the area who want to enhance their techniques.

Contents: Introduction.- Mathematical Preliminaries.- Basic Concepts in Mechanics.- An Introduction to Geometric Control Theory.- Nonholonomic Mechanics.- Controllability and Stabilizability for Mechanical and Nonholonomic Systems.- Optimal Control.- Energy Based Methods for Stability of Nonholonomic Systems.- Energy Based Methods for Stabilization of Controlled Lagrangian Systems.- Internet Supplementary Materials.- References.

Series: Interdisciplinary Applied Mathematics. Volume. 24